1. Single-dose treatment approved for sleeping sickness (www.nature.com)
    14 points by bookofjoe about 13 hours | discuss
  2. M5 Max MacBook Pro Review: Preeminent Power in the Same Old Shell (gizmodo.com)
    8 points by behnamoh about 10 hours | 7 comments
  3. Worming out molecular secrets behind collective behaviour (iisc.ac.in)
    13 points by rainhacker 4 days | discuss
  4. Some Words on WigglyPaint (beyondloom.com)
    acrylic paintdiy craftshandmade art
    119 points by RebelPotato 4 days | 24 comments
  5. Pushing and Pulling: Three reactivity algorithms (jonathan-frere.com)
    reactive systemsalgorithm designdistributed programming
    125 points by frogulis 3 days | 21 comments
  6. Plasma Bigscreen – 10-foot interface for KDE plasma (plasma-bigscreen.org)
    kde plasma desktoplinux interfaceplasma design
    668 points by PaulHoule 4 days | 225 comments
  7. How to run Qwen 3.5 locally (unsloth.ai)
    q&a software developmentlocal developmentgwen 3.5
    487 points by Curiositry 3 days | 163 comments
  8. FLASH radiotherapy's bold approach to cancer treatment (spectrum.ieee.org)
    cancer treatmentimmunotherapytumor microenvironment
    227 points by marc__1 4 days | 73 comments
  9. Show HN: Hopalong Attractor. An old classic with a new perspective in 3D (github.com)
    23 points by ratwolf 5 days | 2 comments
  10. EVi, a Hard-Fork of Vim (codeberg.org)
    vimemacstext editor
    44 points by todsacerdoti about 22 hours | 62 comments
  11. LibreOffice Writer now supports Markdown (blog.documentfoundation.org)
    markdown editing toolslibreoffice writer featuresopen source office software
    401 points by todsacerdoti 3 days | 81 comments
  12. GLP-1 drugs push U.S. consumers toward spicy foods, lifting sauce makers (www.reuters.com)
    8 points by petethomas about 9 hours | discuss
  13. Log4j – Addressing AI-slop in security reports (github.com)
    4 points by tchalla about 9 hours | 1 comments
  14. MonoGame: A .NET framework for making cross-platform games (github.com)
    .net game developmentcross-platform gamingmonogame framework
    111 points by azhenley 3 days | 71 comments
  15. NASA and SpaceX disagree about manual controls for lunar lander (arstechnica.com)
    9 points by voxadam about 14 hours | 2 comments
  16. SHOW HN: A usage circuit breaker for Cloudflare Workers
    17 points by ethan_zhao about 19 hours | 7 comments
  17. Microsoft uses plagiarized AI slop flowchart to explain how GitHub works (www.pcgamer.com)
    7 points by gpvos about 4 hours | 3 comments
  18. Show HN: I built a site where strangers leave kind voice notes for each other (kindvoicenotes.com)
    kindnesscommunitymental health
    57 points by thepaulthomson 2 days | 38 comments
  19. Sem – Semantic version control. Entity-level diffs on top of Git (github.com)
    semantic version controlgit extensionsentity-level diffs
    94 points by pabs3 3 days | 24 comments
  20. Living human brain cells play DOOM on a CL1 [video] (www.youtube.com)
    doom game developmenthuman brain cellscomputational neuroscience
    254 points by kevinak 3 days | 273 comments
  21. A useless infinite scroll experiment (futile.ch)
    81 points by dolin_ch 5 days | 61 comments
  22. Yoghurt delivery women combatting loneliness in Japan (www.bbc.com)
    lonelinessjapanelderly care
    396 points by ranit 4 days | 201 comments
  23. The legendary Mojave Phone Booth is back (2013) (dailydot.com)
    47 points by 1970-01-01 4 days | 9 comments
  24. Ask HN: How to be alone?
    670 points by sillysaurusx 3 days | 552 comments
  25. Will Claude Code ruin our team? (justinjackson.ca)
    software developmentcode maintenanceteam collaboration
    113 points by YounesDz 3 days | 111 comments
  26. Apple's 512GB Mac Studio vanishes, a quiet acknowledgment of the RAM shortage (arstechnica.com)
    ram shortageapple productstech industry
    389 points by rbanffy 3 days | 248 comments
  27. What if the Hormuz closure will not be brief? (www.lloydslist.com)
    strait of hormuz closuremiddle east shippingglobal trade disruptions
    115 points by everybodyknows 3 days | 229 comments
  28. Germany's Solar Boom Eases Power Costs as Gas Price Jumps (www.bloomberg.com)
    solar energyrenewable powergermany energy policy
    83 points by toomuchtodo about 19 hours | 79 comments
  29. We should revisit literate programming in the agent era (silly.business)
    literate programmingsoftware developmentartificial intelligence
    291 points by horseradish 3 days | 250 comments
  30. China's first moon astronauts could land in Rimae Bode (www.space.com)
    4 points by jithinraj about 3 hours | discuss
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